DALACIN C is indicated in serious infections caused by susceptible Gram-positive organisms, staphylococci (both penicillinase- and non-penicillinase-producing), streptococci (except Streptococcusfaecalis) and pneumococci. It is also indicated for serious infections caused by susceptible anaerobic pathogens. Infections due to sensitive organisms which respond to an effective dose of this oral preparation include infections of the:
-Upper respiratory tract including pharyngitis, tonsillitis, sinusitis, otitis media.
-Lower respiratory tract including bronchitis and pneumonia.
-Skin and soft tissue including abscesses, cellulitis, infected wounds, and dental infections (periapical abscesses and gingivitis).
-Bones and joints including acute and chronic osteomyelitis.
Dosage
Adults
Mild to moderately severe infections: 150 mg approximately every six hours.
Severe infections: Up to 450 mg every six hours.
Children
8 - 12 mg/kg/day divided into 3 or 4 equal doses.
Moderately severe infections: 13 - 16 mg/kg/day divided into 3 or 4 equal doses.
Severe infections: 17 - 25 mg/kg/day divided into 3 or 4 equal doses.
DALACIN C capsules should only be used for children who are able to swallow capsules. Do not give DALACIN C capsules to children weighing less than 10 kg. The use of whole capsules may not be suitable to provide the exact mg/kg doses required for the treatment of children.
Capsules should be taken with a full glass of water to avoid the possibility of oesophageal irritation. The capsules must be swallowed whole and not chewed, crushed or opened because of unpleasant taste and possible buccal and oesophageal irritation.
Absorption of DALACIN C is not appreciably modified by the presence of food.
Precautions
Patients with known hypersensitivity to clindamycin, lincomycin or doxorubicin or to any of the excipients of DALACIN C .
Patients with diarrhoeal states or gastrointestinal disease, particularly those with a history of colitis.
Safety for use in pregnancy has not been established.
Clindamycin has been reported to appear in breast milk. Do not use in lactation
DALACIN C contains lactose. Patients with rare hereditary problems of galactose intolerance, total lactase deficiency or glucose-galactose malabsorption should not take this medicine.
