DayQuil/NyQuil Severe Cough Cold & Flu LiquiCaps is a maximum-strength combination over-the-counter medication designed for around-the-clock management of severe cold and flu symptoms. This convenience combo pack typically contains 16 daytime DayQuil LiquiCaps and 8 nighttime NyQuil LiquiCaps to provide fast multi-symptom relief while helping you rest.
Active Ingredients Per Dose (2 LiquiCaps)
The "Severe" formula includes an added expectorant in the daytime capsules and a nasal decongestant in both to tackle heavy congestion:
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Active Ingredient
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DayQuil Severe (Daytime / Non-Drowsy)
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NyQuil Severe (Nighttime / Sleep Aid)
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Purpose / Function
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Acetaminophen
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650 mg
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650 mg
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Reduces fever, relieves sore throat, headaches, and body aches.
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Dextromethorphan HBr
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20 mg
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20 mg
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Suppresses coughing by calming the cough reflex.
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Phenylephrine HCl
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10 mg
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10 mg
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Clears sinus congestion and relieves nasal pressure.
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Guaifenesin
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400 mg
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None
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Expectorant that thins bronchial secretions and loosens mucus.
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Doxylamine Succinate
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None
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12.5 mg
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Antihistamine that dries a runny nose/sneezing and causes drowsiness.
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Symptoms Relieved
This multi-symptom combination formula treats 9 of your worst cold and flu symptoms:
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Fever and chills
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Nasal and sinus congestion
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Severe cough
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Sinus pressure
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Chest congestion (DayQuil only)
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Sore throat
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Headache
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Minor body aches and pains
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Runny nose and sneezing (NyQuil only)
Dosage and Directions
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Age Limit: Adults and children 12 years of age and older.
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Dose: Take 2 LiquiCaps with water.
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Frequency: Every 4 hours as needed.
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Daily Maximum: Do not exceed 8 LiquiCaps (4 doses) in any 24-hour window.
Critical Safety Warnings
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Liver Warning: Both variations contain Acetaminophen. Severe liver damage can occur if you exceed the maximum daily dose, take it with other acetaminophen-containing medications, or consume 3 or more alcoholic drinks daily while using it.
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Drowsiness: NyQuil contains a sedating antihistamine. Do not drive, operate machinery, or perform tasks requiring alertness after taking the nighttime formula.
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Drug Interactions: Consult a doctor before use if you are currently taking blood-thinning medications or a Monoamine Oxidase Inhibitor (MAOI).
