Dermazine cream has a broad antibacterial spectrum including virtually all microbial species likely to infect the wound: E coli, Pseudomonas aeruginosa, Staphylococcus aureus, strains of Proteus and Klebsiella, it is also effective against candida albicans and other fungi. Silver sulphadiazine disintegrates in the burn wound thereby causing a slow and sustained release of silver ions. Silver ions bind to the bacterial desoxyribonucleic acid, thus inhibiting the growth and multiplication of bacterial cells and subcutaneous tissue.
