DIFLUCAN® ONE contains its active ingredient fluconazole 150 mg as capsule given orally, it is indicated for vaginal candidiasis and is administered orally.
Use in Adults
For vaginal candidiasis, fluconazole 150 mg (DIFLUCAN® ONE) should be
administered as a single oral dose.
The median time to onset of symptom relief following a 150 mg single oral dose for the
treatment of vaginal candidiasis is one day. The range of time to onset of symptom
relief is one hour to nine days.
Use in Children
Single dose fluconazole is not recommended for use in children under 18 years of age
except under doctor supervision.
Precautions
Fluconazole has been found in human breast milk at concentrations similar to plasma,
hence its use in nursing mothers is not recommended.
Fluconazole should not be used in patients with known sensitivity to fluconazole; to
related azole compounds; or to any of its excipients.
Co-administration of other drugs known to prolong the QT interval and which are
metabolised via the enzyme CYP3A4 such as cisapride, astemizole, erythromycin,
pimozide and quinidine are contraindicated.
