Domperidone is an antiemetic (anti-sickness) and prokinetic drug. It belongs to a group of drugs called dopamine antagonists. It is used to treat stomach-related issues, such as nausea and vomiting, as well as stomach pain and discomfort caused by decreased movement of the stomach and upper gastrointestinal (GI) tract. It is also used to boost breastmilk supply.
Dosage
Domperidone should be used at the lowest effective dose in adults and adolescents 12 years of age and older and a body weight of 35kg or more.
The usual dose is 10 ml taken up to three times per day, if possible before meals. Do not take more than 30 ml per day.
It is recommended to take oral domperidone 15 to 30 minutes before meals, as when taken after meals the absorption of the medicine is slightly delayed.
Gastric symptoms usually resolve within 3-4 days of using this medicine. Do not take for more than 7 days without talking to your doctor.
Caution
Domperidone may cause an increased risk of heart rhythm disorder and cardiac arrest. This risk may be more likely in those over 60 years old or taking doses higher than 30 mg per day. The risk also increases when it is given together with some drugs.
