Duphaston 10 mg Tablet is an artificial synthetic substitute of progesterone, a female hormone naturally produced by the body. It has the similar action to that of female hormone. This is a steroidal progestin. It contains Dydrogesterone as an active ingredient. Duphaston 10 mg Tablet works by reducing the growth of the endometrium. The drug activates the progesterone receptors, which in turn helps normal shedding of the womb cells and promotes healthy growth.
Duphaston 10 mg Tablet is helpful against dysfunctional uterine bleeding and irregular cycles, hormone replacement therapy, abortion, miscarriage, infertility, premenstrual syndrome, recurring miscarriage due to progesterone deficiency and many other conditions.
How to use
Method of administration: For oral use. For administration of higher doses the tablets should be taken in divided doses over the day.
Posology: The following dosage regimens are recommended for treatment with Duphaston. The quantities can be adjusted according to the seriousness of the disorder to be treated and the individual patients’ responses to the treatment.
Regulation of the cycle: It is possible to achieve a cycle lasting 28 days by giving 1 tablet of Duphaston a day from the 11th to the 25th day of the cycle.
Endometriosis: 1 to 3 tablets of Duphaston a day from the 5th to the 25th day of the cycle or for the entire cycle. Dosages of 10 mg several times a day should be spread over the day. It is recommended that treatment should start at the highest dose. Dysmenorrhoea 1 to 2 tablets of Duphaston a day from the 5th to the 25th day of the cycle. Dosages of 10 mg several times a day should be spread over the day. It is recommended that treatment should start at the highest dose. Infertility as a result of corpus luteum insufficiency 1 tablet of Duphaston a day from the 14th to the 25th day of the cycle.
Threatened abortion Starting dose: 4 tablets of Duphaston at once followed by 1 tablet of Duphaston mg every 8 hours. Dosages of 10 mg several times a day should be spread over the day. It is recommended that treatment should start at the highest dose. If the symptoms persist or recur during the treatment, the dose should be increased by 1 tablet of Duphaston every 8 hours.The effective dose should be maintained for one week after symptoms have ceased; it can then be gradually reduced. If the symptoms recur, the treatment should be resumed immediately at the effective dose.
Habitual abortion 1 tablet of Duphaston a day up to the 20th week of pregnancy; the dose can then be gradually reduced. Treatment should preferably be started before conception. If the symptoms of threatened abortion occur during treatment, treatment should be continued as described for that indication.
Precautions
This medicine is not recommended for use in patients below 18 years of age. It is also not recommended to the pregnant or breastfeeding women. The patient must ensure that the treatment is completed as it should not be stopped in between without consulting the doctor.