Gabbroral 250 mg is an antibiotic and anti-parasitic medication formulated in a 12-tablet pack. It contains paromomycin sulfate (also known as aminosidine sulphate) as its active ingredient. This medication acts locally within the gastrointestinal tract to destroy specific bacteria and amoebic parasites.
Primary Therapeutic Indications
Gabbroral 250 mg targets gut-localized infections:
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Protozoal Infections: Treating acute or chronic intestinal amoebiasis, giardiasis, and cryptosporidiosis.
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Tapeworm Infestations: Clearing intestinal cestodiasis caused by various human tapeworms.
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Hepatic Encephalopathy: Used as an adjunctive treatment to suppress ammonia-producing gut bacteria during hepatic coma.
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Pre-operative Preparation: Sterilizing the intestinal flora immediately before elective gastrointestinal surgery.
Dosing & Administration
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With Food: Paromomycin must be taken with or immediately after meals to minimize stomach distress when treating gut infections.
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Amoebiasis Routine: The typical adult and pediatric dose is 25 to 35 mg/kg of body weight daily, split evenly into 3 doses for 5 to 10 days.
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Complete the Course: You must finish the entire duration prescribed by your doctor, even if your digestive symptoms disappear early, to prevent antibiotic resistance.
Critical Precautions & Side Effects
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Contraindications: Do not take this medication if you suffer from a bowel obstruction or possess a known allergy to aminoglycoside antibiotics.
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Ulcerative Lesions: Use with extreme caution if you have ulcerative colitis or open intestinal wounds. Damage to the gut wall may allow the drug to leak into the bloodstream, increasing the risk of kidney or hearing toxicity.
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Side Effects: Commonly causes mild gastrointestinal discomfort, including nausea, abdominal cramps, vomiting, or temporary mild diarrhea. Report bloody or severe, watery diarrhea to a doctor immediately.
