Leucorin 15mg is a prescription medication containing leucovorin calcium (also known as folinic acid), which is an active form of Vitamin B9. It is primarily used as a "rescue" therapy to prevent or treat the toxic side effects of methotrexate (an anti-cancer and immunosuppressant drug) and to treat specific types of anemia caused by folate deficiency.
Primary Uses
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Methotrexate Rescue: Protects healthy cells from harmful effects after high-dose methotrexate chemotherapy.
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Overdose Treatment: Counteracts accidental overdoses of methotrexate or other folate antagonists.
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Folate Deficiency: Treats megaloblastic anemia when standard folic acid therapy is not sufficient.
Key Drug Facts
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Active Ingredient: Each tablet contains 15mg of folinic acid (derived from calcium folinate).
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Administration: Can be taken by mouth with or without food. For individuals who struggle to swallow tablets, it can be crushed into soft food or dissolved in a liquid immediately before consumption.
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Timing: When used for methotrexate rescue, it is critical to take this medication exactly at the times scheduled by your oncologist (often starting 24 hours after the methotrexate dose).
Potential Side Effects
While generally well-tolerated when used as prescribed, some individuals may experience:
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Nausea, vomiting, or an upset stomach
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Diarrhoea or decreased appetite
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Mouth irritation or sores
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Allergic reactions (such as rash, itching, or hives)
Critical Safety Warnings
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Drug Interactions: Inform your healthcare provider if you are taking anti-seizure medications like phenytoin, as Leucorin can decrease their effectiveness and increase seizure risks.
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Medical Supervision: Dosages must be calculated carefully based on your body size, weight, and specific blood laboratory values. Never adjust your dose without strict medical guidance.
