Riborea 500mg Capsules is a prescription medication that contains the active ingredient hydroxyurea, an antimetabolite and anticancer drug. Manufactured by Khandelwal Laboratories, it is primarily used to manage certain blood disorders and specific types of cancers by altering how rapid or abnormal cells grow and divide.
Primary Uses
-
Sickle Cell Anaemia: Stimulates foetal haemoglobin production to prevent red blood cell sickling, reducing painful crises and transfusions.
-
Chronic Myeloid Leukaemia (CML) & Polycythaemia Vera: Controls the overproduction of abnormal white and red blood cells.
-
Solid Tumours: Used in combination chemotherapy for head, neck, cervical, ovarian, and skin cancers.
How It Works
As a ribonucleotide reductase inhibitor, it blocks DNA synthesis to halt the rapid replication of abnormal cells.
Common Side Effects & Safety Warnings
Requires careful monitoring and regular blood tests.
-
Side Effects: Nausea, vomiting, stomach upset, hair thinning, and dizziness.
-
Precautions: Can cause bone marrow suppression. It is contraindicated during pregnancy and breastfeeding. Report pre-existing kidney, liver, or immune conditions.
General Usage Advice
Take as prescribed, ideally at the same time daily with water, and maintain adequate hydration.