Susten 400mg is a prescription medication that contains natural micronized progesterone, a vital female sex hormone. It is primarily prescribed to treat conditions caused by hormonal imbalances, support reproductive health, and maintain early pregnancies.
Primary Medical Uses
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Female Infertility: It prepares the uterine lining (endometrium) to allow a fertilized egg to implant and supports the luteal phase during assisted reproductive technology (ART/IVF) cycles.
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Pregnancy Support: It helps prevent threatened miscarriages, recurrent abortions, and preterm labor by relaxing the uterus and maintaining the uterine lining.
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Menstrual Disorders: It treats secondary amenorrhea (absence of periods for 3+ months) and regulates irregular or abnormal uterine bleeding.
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Hormone Replacement Therapy (HRT): When combined with estrogen, it protects the uterine lining from overgrowth (endometrial hyperplasia) and manages menopausal symptoms like hot flashes.
How to Take It
Susten 400mg is highly versatile and comes in various formulations—such as oral capsules, soft gelatin capsules, or sustained-release (SR) tablets. Depending on your formulation and specific medical condition, your doctor will advise one of three routes:
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Oral: Swallowed whole with water. Taking it with food can enhance its absorption.
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Vaginal: Inserted deep into the vagina, often using an applicator or your fingers, which reduces systemic side effects like dizziness.
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Rectal: Administered rectally if oral or vaginal routes are not tolerated.
Note: Always use this medication exactly as directed by your healthcare provider, and try to take it at the same time every day to keep your hormone levels stable.
Common Side Effects
Most side effects are temporary and disappear as your body adapts to the hormone:
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Headaches and dizziness
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Nausea, bloating, or stomach cramps
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Breast pain or tenderness
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Drowsiness or fatigue (more common when taken orally)
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Irregular vaginal bleeding or spotting
Important Warnings & Contraindications
Do not take Susten 400mg without a doctor's explicit clearance if you have a history of:
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Unexplained or untreated abnormal vaginal bleeding
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Breast or genital track cancers
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Active or past blood clotting disorders (e.g., deep vein thrombosis, stroke, or heart attack)
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Severe liver disease
