Tylenol Cold + Flu Severe Day & Night Caplets is an over-the-counter multi-symptom medication packaged in a 24-count combination pack containing 16 Daytime and 8 Nighttime caplets. It is formulated for adults and children 12 years and older to temporarily relieve symptoms like fever, cough, congestion, and body aches.
Active Ingredients & Purpose
Both formulas share baseline relief ingredients, but the Day formula targets mucus clearing while the Night formula relieves runny nose and helps you rest.
|
Symptom Target
|
Daytime Caplets (16 count)
|
Nighttime Caplets (8 count)
|
|
Pain & Fever
|
Acetaminophen (325 mg)
|
Acetaminophen (325 mg)
|
|
Nasal Congestion
|
Phenylephrine HCl (5 mg)
|
Phenylephrine HCl (5 mg)
|
|
Cough Suppressant
|
Dextromethorphan HBr (10 mg)
|
Dextromethorphan HBr (10 mg)
|
|
Mucus / Phlegm
|
Guaifenesin (200 mg) — Expectorant
|
None
|
|
Runny Nose & Sneezing
|
None
|
Chlorpheniramine maleate (2 mg) — Antihistamine
|
Standard Dosage Instructions
-
Target Audience: Adults and children 12 years of age and older.
-
Dose: Take 2 caplets every 4 hours while symptoms last.
-
Administration: Swallow caplets whole. Do not crush, chew, or dissolve them.
-
Maximum Limit: Do not exceed 10 caplets total within any 24-hour period.
-
Crucial Rule: Never take the Daytime and Nighttime caplets at the exact same time.
Critical Safety Warnings
-
Severe Liver Damage Warning: This product contains acetaminophen. Taking more than 4,000 mg of acetaminophen in 24 hours, mixing it with other drugs containing acetaminophen, or consuming 3 or more alcoholic drinks daily while using it can cause severe liver damage.
-
Drug Interactions: Do not use this product if you are currently taking a prescription Monoamine Oxidase Inhibitor (MAOI), or for 2 weeks after stopping an MAOI drug.
-
Medical Conditions: Consult a physician before use if you have high blood pressure, diabetes, thyroid disease, glaucoma, heart disease, liver issues, or difficulty urinating due to an enlarged prostate.
-
Drowsiness: The Nighttime formula contains an antihistamine that may cause significant drowsiness. Avoid driving or operating heavy machinery after taking a Nighttime dose.
